Miguel A Lanaspa Selected Research

fructokinase

2/2021	Osthol Ameliorates Kidney Damage and Metabolic Syndrome Induced by a High-Fat/High-Sugar Diet.
1/2020	Sugar causes obesity and metabolic syndrome in mice independently of sweet taste.
1/2020	Deletion of Fructokinase in the Liver or in the Intestine Reveals Differential Effects on Sugar-Induced Metabolic Dysfunction.
1/2019	Endogenous fructose production: what do we know and how relevant is it?
1/2018	High salt intake causes leptin resistance and obesity in mice by stimulating endogenous fructose production and metabolism.
1/2018	Fructose and sugar: A major mediator of non-alcoholic fatty liver disease.
1/2017	Protective role of fructokinase blockade in the pathogenesis of acute kidney injury in mice.
1/2016	Rehydration with soft drink-like beverages exacerbates dehydration and worsens dehydration-associated renal injury.
11/2014	Endogenous fructose production and fructokinase activation mediate renal injury in diabetic nephropathy.
8/2014	Fructokinase activity mediates dehydration-induced renal injury.

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Miguel A Lanaspa Research Topics

Disease

34	Metabolic Syndrome (Dysmetabolic Syndrome X) 05/2022 - 03/2010
29	Obesity 05/2022 - 09/2011
23	Hypertension (High Blood Pressure) 01/2022 - 01/2010
17	Inflammation (Inflammations) 01/2022 - 09/2011
16	Chronic Renal Insufficiency 05/2022 - 03/2010
16	Hyperuricemia 01/2022 - 01/2012
14	Insulin Resistance 01/2022 - 11/2011
13	Fatty Liver 01/2019 - 09/2011
11	Kidney Diseases (Kidney Disease) 02/2021 - 09/2011
10	Gout 01/2021 - 01/2010
9	Non-alcoholic Fatty Liver Disease 01/2021 - 03/2012
9	Dehydration (Water Stress) 01/2020 - 01/2014
8	Acute Kidney Injury (Acute Renal Failure) 01/2020 - 10/2011
7	Fibrosis (Cirrhosis) 10/2021 - 11/2013
6	Cardiovascular Diseases (Cardiovascular Disease) 05/2022 - 02/2015
6	Dyslipidemias (Dyslipidemia) 03/2020 - 01/2017
6	Proteinuria 01/2020 - 05/2012
5	Hypertriglyceridemia 02/2021 - 01/2012
5	Diabetic Nephropathies (Diabetic Nephropathy) 01/2018 - 05/2012
4	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2022 - 01/2016
4	Neoplasms (Cancer) 09/2021 - 09/2017
4	Starvation 09/2021 - 08/2014
4	Type 2 Diabetes Mellitus (MODY) 03/2020 - 09/2011
4	Mitochondrial Diseases (Mitochondrial Disease) 01/2020 - 11/2012
4	Kidney Calculi (Kidney Stone) 01/2020 - 09/2011
3	Metabolic Diseases (Metabolic Disease) 01/2019 - 09/2017
3	Abdominal Obesity 09/2017 - 01/2013
2	Neoplasm Metastasis (Metastasis) 09/2021 - 01/2020
2	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 05/2021 - 09/2011
2	Body Weight (Weight, Body) 02/2021 - 01/2013
2	Hyperglycemia 02/2021 - 11/2016
2	Crystalluria 01/2021 - 01/2016
2	Hypoxia (Hypoxemia) 01/2021 - 01/2018
2	Vascular Calcification 11/2020 - 01/2020
2	Essential Hypertension 01/2020 - 01/2019
2	Overnutrition 01/2018 - 06/2015
2	Tumor Lysis Syndrome 01/2018 - 03/2014
2	Nephrotic Syndrome (Syndrome, Nephrotic) 01/2018 - 01/2018
2	Albuminuria 01/2017 - 01/2016
1	Atrial Remodeling 07/2022
1	Myocardial Infarction 01/2022
1	Pathologic Processes 01/2022
1	Diabetic Ketoacidosis (Ketoacidosis, Diabetic) 01/2022
1	Ischemia 10/2021
1	Bipolar Disorder (Manic Depressive Psychosis) 05/2021
1	Mania (Manias) 05/2021
1	Mood Disorders (Mood Disorder) 05/2021
1	Noncommunicable Diseases 01/2021

Drug/Important Bio-Agent (IBA)

55	FructoseIBA 05/2022 - 03/2010
51	Uric Acid (Urate)IBA 07/2022 - 01/2010
24	SugarsIBA 05/2021 - 09/2011
17	fructokinaseIBA 02/2021 - 09/2011
15	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 03/2010
12	SaltsIBA 01/2021 - 01/2014
8	polyolIBA 05/2022 - 01/2014
8	Urate Oxidase (Uricase)IBA 09/2021 - 09/2011
7	Sucrose (Saccharose)IBA 01/2019 - 09/2011
6	EnzymesIBA 02/2021 - 02/2013
5	CarbohydratesIBA 05/2021 - 11/2011
5	Proteins (Proteins, Gene)FDA Link 01/2021 - 02/2013
5	SodiumIBA 05/2020 - 02/2015
5	Insulin (Novolin)FDA Link 01/2020 - 01/2013
5	Adenosine Triphosphate (ATP)IBA 10/2019 - 01/2012
5	High Fructose Corn SyrupIBA 01/2019 - 10/2013
4	Vasopressins (Vasopressin)IBA 05/2022 - 01/2014
4	NucleotidesIBA 01/2021 - 01/2012
4	Blood Glucose (Blood Sugar)IBA 05/2020 - 05/2012
4	Aldehyde Reductase (Aldose Reductase)IBA 01/2019 - 01/2013
3	ketohexokinaseIBA 02/2021 - 01/2018
3	LipidsIBA 01/2021 - 11/2011
3	LeptinIBA 01/2021 - 01/2018
3	Oxygen (Dioxygen)IBA 01/2021 - 01/2020
3	Sodium-Glucose Transporter 2 InhibitorsIBA 01/2021 - 11/2016
3	CreatinineIBA 01/2020 - 08/2014
3	Xanthine OxidaseIBA 01/2020 - 01/2018
3	Phosphates (Orthophosphate)IBA 10/2019 - 08/2014
3	HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA 01/2019 - 01/2014
3	Triglycerides (Triacylglycerol)IBA 11/2016 - 03/2013
2	InflammasomesIBA 07/2022 - 01/2018
2	Amino Acids FDA Link 01/2022 - 01/2021
2	purineIBA 01/2021 - 04/2016
2	AMP Deaminase (Myoadenylate Deaminase)IBA 01/2021 - 01/2012
2	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 03/2020 - 01/2019
2	Adenosine Monophosphate (AMP)IBA 01/2020 - 01/2012
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2020 - 01/2020
2	AlbuminsIBA 12/2019 - 01/2016
2	ORALIT (ORS)IBA 01/2019 - 01/2018
2	Dietary Sucrose (Table Sugar)IBA 11/2018 - 10/2013
2	HDL CholesterolIBA 01/2018 - 04/2013
2	Protein Isoforms (Isoforms)IBA 01/2018 - 03/2012
2	CalciumIBA 09/2017 - 01/2016
2	Catechin (Z 7300)IBA 11/2016 - 11/2012
2	Streptozocin (Streptozotocin)FDA Link 11/2014 - 05/2012
2	Adenylate KinaseIBA 08/2014 - 01/2012
1	NAD (NADH)IBA 01/2022
1	SirtuinsIBA 01/2022
1	osthol (osthole)IBA 02/2021
1	Aconitate Hydratase (Aconitase)IBA 01/2021

Therapy/Procedure

8	Therapeutics 01/2021 - 05/2012
2	Fluid Therapy (Oral Rehydration Therapy) 01/2018 - 01/2016